Addictive Drugs

The drugs listed on this page are only a sampling of the most commonly used and abused drugs. There are literally thousands of illegal prescription drugs and over-the-counter drugs available. However, the list below has all the classifications. All drugs, prescribed or illicitly obtained will fall within one of the classifications listed below.

It should be noted that all drugs affect the brain and the body. These alterations can be lifesaving, as in easing someone’s pain, anxiety, tremors etc. Taken as prescribed, drugs serve a miraculous purpose. Unfortunately, genetic, biological, environmental, and psychological factors can combine to lead to drug dependence and abuse. Once that occurs, professional help will be required to ease withdrawal of the drug from the body, to stop ingesting the drugs, and to maintain abstinence.

What may seem like innocent experimentation at first can swiftly become a life of despair, hopelessness, enslavement, and physical and emotional devastation. No one ever wins the game of Russian roulette with drugs.

The following is a list of the major classes of abused drugs.

Important Definitions:

Tolerance: The repeated exposure to a drug results in diminution of one or more of the drug’s effects over time.

Physical dependence: A state manifested by specific drug-related withdrawal symptoms produced by abrupt cessation, rapid dose reduction, decreasing blood level of the drug , or administration of an antagonist.

Addiction: a primary, chronic, neurobiologic disease, with genetic, psychosocial, and environmental factors. It is characterized by one or more of the following: impaired control over drug use, compulsive use, continued use despite harm, and cravings.
(source: Medical College of Wisconsin, http://www.eperc.mcw.edu/fastFact/ff_95.htm)

Barbiturates

What are Barbiturates?

Barbiturates are a class of drug that has a direct impact on the central nervous system. They are also known as sedative-hypnotics. They are used to ease anxiety, to induce sleep, for pre-surgical preparation, and to control convulsions. They can be classified as ultra-short, short, intermediate and long acting drug. This class of drugs comes in capsule, tablet, liquid, and injectable forms. The most popular dosages are the intermediate acting barbiturates. Barbiturates are not as popular these days since benzodiazepines were introduced.

Sometimes people who are abusing other drugs, such as cocaine and methamphetamines, will also use barbiturates to help them calm down from their stimulant use. This pattern of using stimulants to “get up” and barbiturates to “come down” becomes addictive. Serious health consequences accompany this combination of drug addiction.

Sign and Symptoms of Barbiturate Intoxication

Common Drugs under the Barbiturate Classification:

  • Fioricet, (butalbital)
  • Nembutal, (pentobarbital)
  • Luminal, (Phenobarbital)
  • Seconal, (secobarbital)
  • Lotusate, (talbuta

Cocaine

What is cocaine?
Cocaine is a central nervous system stimulant. It was first used in the late 1800s as an surgical anesthetic. Cocaine is derived from the leaves of the coca bush. In North America, it is most commonly used in a white powder form extracted from coca leaves. In the United States, cocaine ranks just under marijuana in usage. The substance bought on the streets is a mixture of “pure cocaine and other substances, such as talc, flour, laxatives, sugar, local anesthetics, and other stimulants.”
(source: Florida State Department of Children and Family Services)

Cocaine can be ingested in four manners: by smoking, snorting, or injecting it. The coca leaves can also be chewed. Smoking and injecting cocaine brings it instantly into the blood stream.

The intensity of the high depends upon the speed of absorption into the body. The faster the drug is absorbed into the body, the more intense the high but the effects last only minutes. Cocaine is highly addictive. Some people binge on cocaine, as people do with alcohol.  This behavior usually involves ever increasing amounts of cocaine and can lead to a psychotic break.

Symptoms of Cocaine Abuse
No matter how cocaine is taken, it is dangerous. Some of the most common health problems include:

  • Heart problems, including heart attacks
  • Respiratory effects, including respiratory failure
  • Nervous system problems, including strokes
  • Digestive problems
  • Infectious diseases
    (source: MedlinePlus, http://www.nlm.nih.gov/medlineplus/cocaine.html)
    (read more under quick drug guide)

Ecstasy

What is Ecstasy?
Ecstasy, or MDMA as it is also known, is a synthetic drug first patented in the early 1900s. It is a combination of drugs that have properties of both a hallucinogen and a stimulant. MDMA interferes with the brain’s serotonin production, which regulates mood, aggression, sexual activity, sleep, and sensitivity to pain. When taken it orally in capsule or tablet form, the effects can last between four and six hours.  

Today, it is common for an ecstasy tablet to be combined with other drugs increasing the dangerous side effects on the body and the psyche. Individuals use ecstasy to gain a sense of total well-being, enhanced pleasure from sensory experiences, euphoric feelings, and sociability. It is commonly believed that ecstasy is safe. Ecstasy is a dangerous drug with dangerous and long term side effects.

Signs and Symptoms of an Ecstasy High

  • Increased wakefulness
  • Euphoria
  • Heightened sensory perception
  • Sociability
  • Increased empathy

A Few Symptoms of Frequent Ecstasy Use

  • Hyperactivity
  • Insomnia
  • Anxiety
  • Flight of ideas

Regular use of ecstasy can disrupt cognitive functions, including memory. The drug can be addictive and recovery requires therapy, abstinence, and learning new coping skills. Read more.

Hallucinogens

Hallucinogens are either derived naturally from a plant, or they are created synthetically. Hallucinogens come in a variety of forms: solid, liquid, crystal, plant, extract, and powder. Regardless of the form, hallucinogens cause altered states of perception. People can see, hear, and feel sensations that are not real, but are perceived as real. Some hallucinogens were developed to be used as anesthetic. While these drugs are sometimes considered hallucinogens because they alter perception, they are more accurately known as dissociative anesthetics, or DA.
These are the most commonly used and known hallucinogens:

  • LSD
  • Ecstasy
  • PCP (DA)
  • Mushrooms, peyote and mescaline, psilocybin, ibogaine
  • Ketamine (DA)
  • Dextromethorphan (cough suppressing ingredient)

Signs and Symptoms of Hallucinogens

  • Distorted sense of time
  • Visual delusions
  • Cross of senses (seeing sounds, hearing colors)

Negative Impact of Hallucinogens

  • Increased heart rate
  • Sweating
  • Depression
  • Difficulty speaking
  • Weight loss
  • Vomiting
  • Loss of muscular coordination
  • Violence and/or suicidal ideation
  • Dry mouth
  • Tremors
  • Sleeplessness
  • Mimics schizophrenia
  • Intense emotional swings

The effects of hallucinogens can last from six to twenty four hours. These altered experiences are unpredictable, making each episode highly volatile; what can be exciting and fun one moment can quickly turn nightmarish the next. Flashbacks can persist and impair social or occupational functioning. A bad trip can continue to plague the user for years. This is a condition known as hallucinogen-induced persisting perceptual disorder (HPPD). (source: NIDA)

Some of the hallucinogens, if taken regularly, can cause the body and psyche to build a tolerance, as happens with and Ecstasy. 

Inhalants

Inhalants are chemical substances that are inhaled. These chemicals are found in common household items and come in a number of forms:

  • Volatile solvents (industrial lighter fluid, gasoline, cleaners, markers, glue)
  • Aerosols (spray paint, fabric protector, hairspray)
  • Gases (whipped cream, butane, anesthesia gases)
  • Nitrites (poppers, butyl, amyl nitrites)

The chemicals inhaled are quickly absorbed into the bloodstream and then immediately transferred to the brain. The amount of inhalant taken into the body over a specific period of time will determine the overall effect. Initial absorption of an inhalant can manifest immediately with the loss of coordination and balance. After an hour the body absorbs the chemicals into the skin, muscles, and fat cells.
The biggest effect of inhalants is rapid intoxication and unconsciousness. It mimics alcohol inebriation. It is a three-minute “high,” so the user continuously repeats the process.  

Signs and Symptoms of Inhalant Abuse

  • Loss of sensation
  • Unconsciousness
  • Hearing loss (may be irreversible)
  • Limb spasms
  • Brain damage
  • Slurred speech
  • Dizziness
  • Heart failure (when large quantities are inhaled)
  • Loss of appetite
  • Facial rashes and blisters
  • Agitation

Sudden “sniffing death” is the most common form of death from inhalant use. The body is unable to assimilate the chemicals, which makes heart regulation difficult and results in cardiac arrest. Sniffing death is not the only way to die from inhalants:

Amphetamines

Amphetamines are a class of drugs that act as stimulants in the body. Prescription drugs and OTC drugs in this classification are most notable for their alerting, anti-fatigue, sleep-suppressing, and performance-enhancing properties. Studies have demonstrated that one in nine people who use prescription stimulants for purposes other than as prescribed will become addicted. (source: American Society of Addiction Medicine, 2003, pp.165-66)


Amphetamines have been demonstrated to increase aggressive behavior even when low dosages are regularly taken. Studies have also shown a high rate of stimulant abuse among those convicted of violent crimes. (American Society of Addiction Medicine, 2003, p.167)

The serious negative impact upon a person’s body can override any positive medicinal uses of the drugs if they are abused.

Signs and Symptoms of Amphetamine Abuse

 

  • Anxiety
  • Panic
  • Interpersonal sensitivity
  • Stimulant induced hallucinations
  • Restlessness
  • Tremors
  • Repetitive behaviors such as picking at one’s teeth
  • Cognitive impairment
  • Psychotic flashbacks with methamphetamine
  • Dental problems with methamphetamine

Commonly known Amphetamine Drugs

  • Methamphetamine
  • Desoxyn
  • dextroamphetamine, Dexadrine
  • Adderall, Ritalin
  • Methylphenidate, Phentermine, Adipex (amphetamine like substances-diet pills)

Though some people can experience compulsive sexual arousal, the more frequent experience is one of sexual inhibition.

Marijuana

 

What is marijuana?
According to the American Society of Addiction Medicine (2003), there are “over 400 chemicals that are synthesized from the hemp plant approximately 60 of which are cannabinoids”. Marijuana or cannabis has had a long and illustrious history. The use of this plant as a drug dates back thousands of years. “The euphoric properties were discovered in India around 2000 BC, and cannabis was recommended for reducing fever, producing sleep, stimulating the appetite, relieving headaches, and curing venereal disease”.

A great deal of modern research on cannabis and its medicinal properties has resulted in quantifiable evidence that marijuana has pain relieving properties for people undergoing cancer treatment and other major ailments. However, there is a difference in the types of cannabis, how they are administered and the effects upon the body.  Smoking marijuana is not the same as taking the drug orally in a tablet form.  Patients suffering from pain going through cancer treatment, those suffering from AIDS related problems and glaucoma are usually given cannabis oral form. THC also stimulates the appetite.

Some of the more common forms are THC, hashish, and hash oil, and Marinol. All forms of cannabis are psychoactive, mind altering drugs.

Social Impact of Marijuana Abuse

  • Increased absences from school or work
  • Tardiness
  • Accidents
  • Changes in cognitive abilities (memory, reasoning, learning)
  • Disruption of career path
  • Family discord
  • Cough
  • Acute chest illness and heightened risk of lung infections
  • Decrease in sperm mobility and sperm count
  • Interference with ovulation and pre-natal development

There is on-going research examining the link between chronic marijuana use and schizophrenia, especially among young users. (read more Quick DrugGuide)

Steroids

What are anabolic steroids? (AAS)
Anabolic steroids are pure, natural male hormones or are synthetic substances similar to the male sex hormones naturally produced in the body. These hormones are associated with male sexual characteristics and skeletal muscle development. Steroids are converted into testosterone once ingested. Originally, steroids were developed and used to help males suffering from a variety of conditions related to a lack of the male hormones. Quickly, however, the results of enhanced muscle development in rats led to abuse among bodybuilders, weightlifters, and finally other athletes.
In the last several decades, athletes, people working out in gyms, and students have used steroids in hopes of “bulking up” or enhancing athletic performance.

Commonly Used Steroids
Abused Steroids

Oral Steroids
  • Anadrol (oxymetholone)
  • Oxandrin (oxandrolone)
  • Dianabol (methandrostenolone)
  • Winstrol (stanozolol)
Injectable Steroids
  • Deca-Durabolin (nandrolone decanoate)
  • Durabolin (nandrolone phenpropionate)
  • Depo-Testosterone (testosterone cypionate)
  • Equipoise (boldenone undecylenate)
  • Tetrahydrogestrinone (THG)

(source: NIDA, Research Report Series, http://www.drugabuse.gov/ResearchReports/Steroids/anabolicsteroids2.html#anchor)
Signs and Symptoms of Steroid Abuse

  • Early heart attacks
  • Strokes
  • Liver tumors
  • Kidney failure
  • Psychiatric problems
  • HIVAIDS (if injecting and sharing needles)
  • Hepatitis B and C
  • Mood Swings
  • Violence
  • Loss of appetite
  • Insomnia
  • Loss of sex drive

People who use steroids will often engage in “cycling” a pattern of using steroids for a period of weeks or months followed by a short period of time without the drugs. Other users will combine different types of steroids to get the maximum impact upon the body. Regardless, of the specific pattern of use, there are adverse influences upon the entire body.

The Use of Anabolic-Androgenic Steroids on the Brain
Steroids do not produce a “high”. But research data indicates that the same dopamine, serotonin and opioid (used to combat pain) receptors are altered and that mood and behavioral changes are seen in those who abuse steroids.

The symptoms of addictive behavior for people who abuse steroids are the same as those of other addictions; these include negative behavioral patterns and financial stress. Animal research illustrates that use among adolescence males and adult males differs with regard to aggression and sexual behaviors, placing adolescent males at greater risk for adverse effects. (source: PubMedCentral, Kaliris Y. Salas-Ramirez, et al, 6/10/10,  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2883314/?report=abstract&tool=pmcentrez )

“AAS abuse appears to be associated with a range of potentially prolonged psychiatric effects, including dependence syndromes, mood syndromes, and progression to other forms of substance abuse…” (source: PubMedCentral, Gen Kanayama, et al., 11/01/09, http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2646607/?report=abstract&tool=pmcentrez)

Research demonstrates that a AAS overdose mimics that of an opioid overdose. Withdrawal symptoms are difficult to manage and should be medically monitored. Electrolyte disturbances can occur. But, one of the most serious side effects of AAS withdrawal is depression, if left untreated it can lead to suicide.

Benzodiazepines

What are benzodiazepines?
Benzodiazepines are a class of drugs that are prescribed to help reduce anxiety and/or to sedate and relax muscles. These drugs work on the central nervous system.

There are three types of benzodiazepines prescribed: short acting, intermediate acting and long acting. The difference applies to how quickly the drug is absorbed into the blood stream and how long it lasts in the system. Of all prescribed drugs, this class of drugs is the most prescribed in the United States.

Types of Short to Intermediate Acting Benzodiazepines

  • estazolam       (ProSom)
  • flurazepam     (Dalmane)
  • temazepam     (Restoril)
  • triazolam        (Halcion, Hypam, Tricam)
  • midazolam     (Versed)
  • zolpidem        (Ambien)
  • bromazepam  (Lexotan)
  • alprzolam       (Xanax)
  • loprazolam     (Dormonoct)
  • lorazepam      (Ativan, Lorapam, Lorzem)
  • lormetazepam (Noctamid)
  • oxazepam       (Serenid, Serepax, Serax, Benzotran, Ox-pam)
  • temazepam     (Euhypnos, Normison, Somapam)

These are used to sedate people before sleep, surgery, anxiety, and for critical care settings.
Side Effects from these Short Term Dosages

  • Impaired motor coordination
  • Drowsiness
  • Impaired thinking
  • Confusion
  • Depression
  • Slurred speech
  • Tremors
  • Nausea
  • Constipation
  • Abdominal discomfort
    (for anxiety)

Intermediate to Long Acting Benzodiazepines

  • chlordiazepoxide  (Librium, Nova-pam)
  • clorazepate           (Tranxene)
  • clobazam              (Frisium)
  • clonazepam          (Rivotril, Klonopin)
  • diazepam              (Valim, D-Pam, Pro-pam)
  • flunitrazepam       (Rohypnol)
  • flurazepam           (Dalmane)
  • medazepam          (Norbium)
  • prazepam              (Centrax)
  • nitrazepam            (Mogadon, Insoma, Nitrados)

These are used to treat severe anxiety or depression
Side Effects from Long Term Dosages

  • Impaired thinking, memory, and judgment
  • Disorientation
  • Confusion
  • Slurred speech
  • Muscle weakness, lack of coordination
  • Accidents
  • Anterograde amnesia

Date Rape Drugs

Some of the drugs in this classification are also known as date rape drugs. Flunitrazepam (Rohypnol), illegal in the United States is one of the better known date rape drugs. Another commonly used date rape drug is GHB.
While it is not specifically a benzodiazepine class drug it mimics the sedative effects of this class of drugs.

Giving someone drugs without their knowledge is illegal. Doping someone’s drink to have sex with them is a serious criminal offense.

Commonly Used Benzodiazepines as Date Rape Drugs

  • Clonazepam
  • Klonopin
  • Rivotril
  • Alprazolam, Xanax

Though not a benzodiazepine, Ketamine is also used as a date rape drug.

Other Drugs that Mimic Benzodiazepines: Sleep Aids
Because all these drugs act upon the central nervous system, they work well as a sleep aid. However, it is also easily abused and quickly becomes addictive. Even over the counter sleep aids can cause disturbance in normal brain function.

Some Prescribed Drugs Used as Sleep Aids

  • eszopicione, Lunesta
  • zaleplon, Sonata
  • zolpidem, Ambien\

Withdrawal Symptoms
Symptoms will vary depending upon the type of drug (short term or long term) dosage, length of time using and other psychological and medical factors.

  • Anxiety (which may be the initial motivation for the drug)
  • Irritability
  • Insomnia
  • Fatigue
  • Headache
  • Twitching
  • Sweating
  • Concentration difficulties
  • Loss of Appetite
  • Increased sensory perception
  • Derealization

Once a cycle of addiction and withdrawal has begun, it can be difficult to break especially when the prescribing doctor is not familiar with addictive patterns.

Opioids (Opiates)

What are Opioids?
Opioids are a class of drugs that act upon the brain and body to relieve pain, in some cases diarrhea, and suppress coughs. Drugs which attach to specific protein receptors in the brain, spinal cord, and the gastrointestinal track are also called opioids. There are three principle opioid receptors in the central nervous system: mu, kappa, and delta. These receptors are used to experience pleasure as well as easing the body’s experience of pain.

There are three groups of opioids:

  • Natural Occurring Opioids
    • codeine
    • morphine, Kadian, MS Contin
    • opium
       
  • Semi-synthetic Opioids
    • heroin
    • buprenorphine (Suboxone, Subutex)
       
  • Synthetic Opioids
    • propoxphene, Darvocet, Darvon
    • butorphahol
    • levorphanol
    • pentazocine
    • meperidine, Demerol
    • fentanyl, Duragesic, Actiq
    • oxycodone, Percocet, Oxcycontin, Roxicodone, Roxicet
    • Endocet, Percodan, Tylox
    • hydrocodone, Lortab, Lorcet, Vicodin
    • hydromorphone, Dilaudid
    • methadone
    • oxymorphone, Opana
    • nalmefene (Revex)
    • naltexone (ReVia)

Areas of the Brain Affected by Opioids

 The diagram above illustrates the three areas of the body that are affected by opioids. Below is a description of the responsibilities of each area.

  1. Limbic System: Controls emotions
  2. The brain stem: Responsible for all automatic functions such as breathing
  3. The spinal cord: Transmits information and sensation throughout the body.
    (source: NIDA for teens: http://teens.drugabuse.gov/mom/mom_opi2.php)

Withdrawal Symptoms of Opioids
Early symptoms of withdrawal include:

  • Agitation
  • Anxiety
  • Muscle aches
  • Increased tearing
  • Insomnia
  • Runny nose
  • Sweating
  • Yawning

Late symptoms of withdrawal include:

  • Abdominal cramping
  • Diarrhea
  • Dilated pupils
  • Goose bumps
  • Nausea
  • Vomiting

Opioid withdrawal reactions are extremely uncomfortable but are not necessarily life threatening, where as dehydration may occur, or heart failure do to the extreme physical stress during detox. Symptoms usually start within 12 hours of last usage. Detox should be supervised by a medical doctor and supporting staff. (source: MedlinePlus, Opiate Withdrawal, http://www.nlm.nih.gov/medlineplus/ency/article/000949.htm)

Drugs that have Properties Like Opiates

  • tramadol, Ultram
  • carisprodol, Soma

Most opiate overdose deaths occur in people who have just withdrawn or detoxed. Returning to drugs immediately following detox is very dangerous the user believes he or she can start at the last dosage. Such a choice increases the likelihood of overdosing because the body cannot absorb the higher level of drugs at one time. Medical detox is strongly advised followed immediately by treatment.

Drugs, regardless of the miracles they perform in helping cope with environmental or psychosocial dilemmas, are dangerous. They need to be taken only as prescribed and never as a form of recreation. Damage from long term or heavy short term use of drugs can cause brain damage, organ damage or organ failure.